what AV do you use ? make sure you add the loader to AV's allowed programs [ exception ] , if you do not have the AV just turn off your firewall and also add the loader to allowed programs thro firewall
Check your DEP and make sure it looks like the pic below. Control panel> system and security> system> advanced system settings> Performance (settings)> Data execution prevention.
For most games to work with the hack, you need to disable User Account Control (UAC). Control Panel > User Accounts > Change User Account Control Settings.